Controlled Substances and Precursor Chemicals Program

Consult the Drug Enforcement Administration (DEA) Registration & Renewal Fact Sheet on the process or visit the DEA Registration and Renewal web page for in-depth information.

1. Go to the DEA website and complete Forms 224 (Practitioner) or 225 (Researcher) depending on your business activity. IMPORTANT NOTE: Notify EH&S if/when DEA Investigators plan a visit to USC. EH&S will attend and assist during the initial inspection.
2. Set up appropriate storage and security in your lab. For assistance, you are welcome to schedule a consultation with EH&S prior to the DEA’s initial visit.
3. After receiving a DEA license, follow these steps:
   • Send a copy of the DEA registration to ehs-cs@usc.edu.
   • Enroll in the USC Controlled Substance Program. Complete the following forms and send copies to ehs-cs@usc.edu.
     • CS Use Authorization Application (Form A)
     • Personnel Screening Data Sheet (Form A-1) for all Authorized Users
     • Initial Inventory (Form C).
4. Ensure completion of required training for Authorized Users.
   • CST Training on Trojan Learn
   • CST Resource Guide (additional CS training e.g., How-To videos, guide sheets)
   • EH&S Safety Training Catalog
5. Prepare for an initial EH&S inspection.

Refer to the links below for information on how to purchase, manage, and maintain CS in the laboratory.

• Purchase
  • CS Purchase Fact Sheet and CS Purchase web page
  • Precursor Chemicals Purchase web page
• Recordkeeping & Inventory – see the Controlled Substances – Recordkeeping & Inventory Guide Sheet and Recordkeeping and Inventory web page.
• Storage and Security – see Storage & Security
• Inspections and Monitoring – CS monitoring and inspections and Illicit Use and Consequences.
• Personnel – Add an Authorized User. NOTE: Personnel must complete all steps below to gain access to controlled substances.
  • Ensure appropriate training (see Registration and Renewal, step 4).
  • Complete Personnel Screening (coming soon).

The following links discuss CS removal.

• Disposal – see information at the Controlled Substances and Precursor Chemical Disposal web page.
• Transfer – follow instructions at the Controlled Substances Transfer web page and complete Form E to initiate the transfer.
• Close a CSUA – refer to the Relocation and Closure web page in tandem with the Move or Close a Lab web page, if applicable (see First Steps).
• Spills or Other Loss – visit Diversion, Theft, or Loss or Spills for information on reporting and cleanup. Use Form F to document a CS incident. If an active theft is in progress, contact DPS at (213) 740-4321.

Forms

• CS Form A – Controlled Substance Use Authorization Application
• CS Form A-1 – Personnel Screening Data Sheet
• CS Form B – Controlled Substance Usage & Disposal Log
• CS Form B-1 – Controlled Substance Dilution Usage & Disposal Log
• CS Form C – Controlled Substance Initial and Annual Physical Inventory
• CS Form E – Controlled Substance Transfer
• CS Form F – Controlled Substance Incident Report
• CS Form G – Controlled Substance Waste Disposal Request
• CS Form H – Controlled Substance Inspections
• Form 222 (Schedule II)
• Site-Specific Training Record (SSTR)

Documents

• Controlled Substances and Precursor Chemicals Fact Sheets
• CS Schedule I-V – alphabetical order
• PC Lists I & II – alphabetical order
• PC California List

Training

• CS Training
• CS Training Resource Guide
• Training Requirements
• Training Catalog
• Course Registration
• Annual Laboratory Safety Refresher Training